This article summarizes the current state of CCI in the industry and describes concepts for defining a best practice CCI testing strategyDownload ⬇
Here is a link to a publication in American Pharmaceutical Review: read the article
Read the November/December PDA Journal article from LIGHTHOUSE Instruments on CCI method development using gaz ingress measurement in the headspace of pharmaceutiocal containers.
The recently updated USP 39 <1207> chapter on Package Integrity recommends a move to deterministic analytical methods for assessing container closure integrity of sterile product packagesDownload ⬇
Comparison of Tunable Diodi Laser Absorption Spectroscopy (headspace measurement) and Isothermal Micro-calorimetry for Non-invasive Detection of Microbial Growth in Media Fills. Published in NATURE on June 10th 2016.Download ⬇
Evaluating Media Fill batches thanks to an oxygen and a carbon dioxyde non destructive headspace measurement. Article from the PDS Journal, May-June 2016.Download ⬇
Headspace Moisture Analysis for Determination of Residual Moisture Content in Lyophilized Pharmaceutical Products.Download ⬇
Publication in the magazine "Doses", the Healthcare Packagin Products Magazine.
No. 63 (April 2016): Article on page 80 PlümatDownload ⬇